Changes in simian immunodeficiency virus reverse transcriptase alleles that appear during infection of macaques enhance infectivity and replication in CD4(+) T cells

We previously showed that a slowly replicating, minimally pathogenic clone of simian immunodeficiency virus (SIV), SIVmneCl8, evolves increased ability to replicate in T cells with the onset of AIDS in pig-tailed macaques. Moreover, molecular clones derived from late stages of infection (SIVmne170 a...

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Hlavní autoři: Biesinger, Tasha, Yu Kimata, Monica T., Kimata, Jason T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196132/
https://ncbi.nlm.nih.gov/pubmed/17904609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.011
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