The PAAD/PYRIN-Family Protein ASC Is a Dual Regulator of a Conserved Step in Nuclear Factor κB Activation Pathways

Apoptosis-associated speck-like protein containing a Caspase recruitment domain (ASC) belongs to a large family of proteins that contain a Pyrin, AIM, ASC, and death domain-like (PAAD) domain (also known as PYRIN, DAPIN, Pyk). Recent data have suggested that ASC functions as an adaptor protein linki...

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Detalhes bibliográficos
Main Authors: Stehlik, Christian, Fiorentino, Loredana, Dorfleutner, Andrea, Bruey, Jean-Marie, Ariza, Eugenia M., Sagara, Junji, Reed, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196065/
https://ncbi.nlm.nih.gov/pubmed/12486103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021552
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