Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid (sHA) produced during inflammation have been shown to be potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages. Here we report that sHA induces maturation of DCs via the Toll-like...

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Bibliographic Details
Main Authors: Termeer, Christian, Benedix, Frauke, Sleeman, Jonathon, Fieber, Christina, Voith, Ursula, Ahrens, Thomas, Miyake, Kensuke, Freudenberg, Marina, Galanos, Christopher, Simon, Jan Christoph
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196009/
https://ncbi.nlm.nih.gov/pubmed/11781369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20001858
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