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The Leishmania infantum Acidic Ribosomal Protein P0 Administered as a DNA Vaccine Confers Protective Immunity to Leishmania major Infection in BALB/c Mice

In this study, we examined the immunogenic properties of the Leishmania infantum acidic ribosomal protein P0 (LiP0) in the BALB/c mouse model. The humoral and cellular responses induced by the administration of the LiP0 antigen, either as soluble recombinant LiP0 (rLiP0) or as a plasmid DNA formulat...

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Autors principals: Iborra, Salvador, Soto, Manuel, Carrión, Javier, Nieto, Ana, Fernández, Edgar, Alonso, Carlos, Requena, Jose M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC219595/
https://ncbi.nlm.nih.gov/pubmed/14573678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6562-6572.2003
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