Cd8 Expression up to the Double-Positive CD3(Low/Intermediate) Stage of Thymic Differentiation Is Sufficient for Development of Peripheral Functional Cytotoxic T Lymphocytes

Control of CD8α transcription during development of α/β T cell receptor (TCR) T lymphocytes is mediated by at least two distinct stage-specific cis-acting transcriptional mechanisms (i.e., enhancers). On the CD8α(−/)−knockout (KO) background, cis-mechanism I and cis-mechanism II together mediate app...

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Detalhes bibliográficos
Principais autores: Zhang, X.-L., Zhao, S., Borenstein, S.H., Liu, Y., Jayabalasingham, B., Chamberlain, J.W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195943/
https://ncbi.nlm.nih.gov/pubmed/11535636
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