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Clustered Mutations in HIV-1 Gag Are Consistently Required for Escape from Hla-B27–Restricted Cytotoxic T Lymphocyte Responses
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an epitope in p24 gag (amino acids 263–272, KRWIILGLNK). Substitution of lysine (K) or glycine (G) for arginine (R) at HIV-1 gag residue 264 (R264...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
The Rockefeller University Press
2001
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2195921/ https://ncbi.nlm.nih.gov/pubmed/11157057 |
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