DNA Immunization with the Gene Encoding P4 Nuclease of Leishmania amazonensis Protects Mice against Cutaneous Leishmaniasis

Infection with the protozoan parasite Leishmania amazonensis can cause diverse clinical forms of leishmaniasis. Immunization with purified P4 nuclease protein has been shown to elicit a protective response in mice challenged with L. amazonensis and L. pifanoi. To explore the potential of a DNA-based...

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Bibliographic Details
Main Authors: Campbell, Kimberly, Diao, Hong, Ji, Jiaxiang, Soong, Lynn
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC219588/
https://ncbi.nlm.nih.gov/pubmed/14573646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6270-6278.2003
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