In Vivo Evidence for the Contribution of Human Histocompatibility Leukocyte Antigen (Hla)-Dq Molecules to the Development of Diabetes

Although DQA1*0301/DQB1*0302 is the human histocompatibility leukocyte antigen (HLA) class II gene most commonly associated with human type 1 diabetes, direct in vivo experimental evidence for its diabetogenic role is lacking. Therefore, we generated C57BL/6 transgenic mice that bear this molecule a...

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Autores principales: Wen, Li, Wong, F. Susan, Tang, Jie, Chen, Ning-Yuan, Altieri, Martha, David, Chella, Flavell, Richard, Sherwin, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195792/
https://ncbi.nlm.nih.gov/pubmed/10620608
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