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Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

In macroautophagy, cytoplasmic components are delivered to lysosomes for degradation via autophagosomes that are formed by closure of cup-shaped isolation membranes. However, how the isolation membranes are formed is poorly understood. We recently found in yeast that a novel ubiquitin-like system, t...

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Detalhes bibliográficos
Main Authors: Mizushima, Noboru, Yamamoto, Akitsugu, Hatano, Masahiko, Kobayashi, Yoshinori, Kabeya, Yukiko, Suzuki, Kuninori, Tokuhisa, Takeshi, Ohsumi, Yoshinori, Yoshimori, Tamotsu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195787/
https://ncbi.nlm.nih.gov/pubmed/11266458
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