Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice

Interleukin (IL)-1 is a proinflammatory cytokine that plays important roles in inflammation, host defense, and the neuro-immuno-endocrine network. IL-1 receptor antagonist (ra) is an endogenous inhibitor of IL-1 and is supposed to regulate IL-1 activity. However, its pathophysiological roles in a bo...

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Detalhes bibliográficos
Main Authors: Horai, Reiko, Saijo, Shinobu, Tanioka, Hidetoshi, Nakae, Susumu, Sudo, Katsuko, Okahara, Akihiko, Ikuse, Toshimi, Asano, Masahide, Iwakura, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195765/
https://ncbi.nlm.nih.gov/pubmed/10637275
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