Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice

Interleukin (IL)-1 is a proinflammatory cytokine that plays important roles in inflammation, host defense, and the neuro-immuno-endocrine network. IL-1 receptor antagonist (ra) is an endogenous inhibitor of IL-1 and is supposed to regulate IL-1 activity. However, its pathophysiological roles in a bo...

Full description

Saved in:
Bibliographic Details
Main Authors: Horai, Reiko, Saijo, Shinobu, Tanioka, Hidetoshi, Nakae, Susumu, Sudo, Katsuko, Okahara, Akihiko, Ikuse, Toshimi, Asano, Masahide, Iwakura, Yoichiro
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195765/
https://ncbi.nlm.nih.gov/pubmed/10637275
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items