Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma

Dendritic cells (DCs) are considered to be promising adjuvants for inducing immunity to cancer. We used mature, monocyte-derived DCs to elicit resistance to malignant melanoma. The DCs were pulsed with Mage-3A1 tumor peptide and a recall antigen, tetanus toxoid or tuberculin. 11 far advanced stage I...

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Detalhes bibliográficos
Main Authors: Thurner, Beatrice, Haendle, Ina, Röder, Claudia, Dieckmann, Detlef, Keikavoussi, Petra, Jonuleit, Helmut, Bender, Armin, Maczek, Christian, Schreiner, Doris, von den Driesch, Peter, Bröcker, Eva B., Steinman, Ralph M., Enk, Alexander, Kämpgen, Eckhart, Schuler, Gerold
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195739/
https://ncbi.nlm.nih.gov/pubmed/10587357
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