Relative Immunogenicity of PorA Subtypes in a Multivalent Neisseria meningitidis Vaccine Is Not Dependent on Presentation Form

The hexavalent meningococcal vaccine HexaMen, containing six PorAs on two vesicles, was tested in clinical studies. Although fourfold increases in serum bactericidal activity (SBA) titers against all of the PorAs were observed, there were significant differences between PorA-specific SBA titers. SBA...

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Bibliographic Details
Main Authors: Luijkx, Thomas A., van Dijken, Harry, Hamstra, Hendrik-Jan, Kuipers, Betsy, van der Ley, Peter, van Alphen, Loek, van den Dobbelsteen, Germie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC219571/
https://ncbi.nlm.nih.gov/pubmed/14573657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6367-6371.2003
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