Outer membrane protein of Neisseria meningitidis as a mucosal adjuvant for lipopolysaccharide of Brucella melitensis in mouse and guinea pig intranasal immunization models.

A mucosal vaccine against brucellosis consisting of the lipopolysaccharide (LPS) of Brucella melitensis complexed with the outer membrane protein (GBOMP) of group B Neisseria meningitidis was tested in small-animal models of intranasal immunization. Mice given two doses of the vaccine developed high...

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Autores principales: Van De Verg, L L, Hartman, A B, Bhattacharjee, A K, Tall, B D, Yuan, L, Sasala, K, Hadfield, T L, Zollinger, W D, Hoover, D L, Warren, R L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC174517/
https://ncbi.nlm.nih.gov/pubmed/8945575
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