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A20 Inhibits Cytokine-Induced Apoptosis and Nuclear Factor κB–Dependent Gene Activation in Islets

Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease resulting from apoptotic destruction of β cells in the islets of Langerhans. Low expression of antioxidants and a predilection to produce nitric oxide (NO) have been shown to underscore β cell apoptosis. With this perspective in min...

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Detalhes bibliográficos
Main Authors: Grey, Shane T., Arvelo, Maria B., Hasenkamp, Wendy, Bach, Fritz H., Ferran, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195658/
https://ncbi.nlm.nih.gov/pubmed/10523611
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