Apoptosis of Human Islet Cells by Cytokines

FasL, perforin, TNFα, IL-1 and NO have been considered as effector molecule(s) leading to β-cell death in autoimmune diabetes. However, the real culprit(s) of β-cell destruction have long been elusive despite intense investigation. Previously we have suggested IFNγ/TNFα synergism as the final effect...

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Autori principali: Kim, Sunshin, Kim, Kyoung-Ah, Suk, Kyoungho, Kim, Yun-Hee, Oh, Seung Hoon, Lee, Moon-Kyu, Kim, Kwang-Won, Lee, Myung-Shik
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Association of Immunologists 2012
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Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422709/
https://ncbi.nlm.nih.gov/pubmed/22916047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2012.12.3.113
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