An Expanded Peripheral T Cell Population to a Cytotoxic T Lymphocyte (Ctl)-Defined, Melanocyte-Specific Antigen in Metastatic Melanoma Patients Impacts on Generation of Peptide-Specific Ctls but Does Not Overcome Tumor Escape from Immune Surveillance in Metastatic Lesions

It is not known if immune response to T cell–defined human histocompatibility leukocyte antigen (HLA) class I–restricted melanoma antigens leads to an expanded peripheral pool of T cells in all patients, affects cytotoxic T lymphocyte (CTL) generation, and correlates with anti-tumor response in meta...

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Detalhes bibliográficos
Main Authors: Anichini, Andrea, Molla, Alessandra, Mortarini, Roberta, Tragni, Gabrina, Bersani, Ilaria, Di Nicola, Massimo, Gianni, Alessandro M., Pilotti, Silvana, Dunbar, Rod, Cerundolo, Vincenzo, Parmiani, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195616/
https://ncbi.nlm.nih.gov/pubmed/10477550
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