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Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment

Surface-expressed immunoglobulin (Ig) has been shown to have a critical role in allelic exclusion of Ig heavy (H) and light (L) chains. Although various degrees of suppression of endogenous Ig expression are observed in Ig transgenic (Tg) mice, it was not clear whether this difference is due to diff...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Watanabe, Norihiko, Nisitani, Sazuku, Ikuta, Koichi, Suzuki, Misao, Chiba, Tsutomu, Honjo, Tasuku
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195600/
https://ncbi.nlm.nih.gov/pubmed/10449517
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