Lung Epithelial Cells and Extracellular Matrix Components Induce Expression of Pneumocystis carinii STE20, a Gene Complementing the Mating and Pseudohyphal Growth Defects of ste20 Mutant Yeast

Pneumocystis carinii causes severe pneumonia in immunocompromised hosts. The binding of P. carinii to alveolar epithelial cells and extracellular matrix constituents such as fibronectin and vitronectin is a central feature of infection, which initiates proliferation of the organism. Herein, we demon...

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Autores principales: Kottom, Theodore J., Köhler, Julia R., Thomas, Charles F., Fink, Gerald R., Limper, Andrew H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC219549/
https://ncbi.nlm.nih.gov/pubmed/14573668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6463-6471.2003
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