Lung Epithelial Cells and Extracellular Matrix Components Induce Expression of Pneumocystis carinii STE20, a Gene Complementing the Mating and Pseudohyphal Growth Defects of ste20 Mutant Yeast

Pneumocystis carinii causes severe pneumonia in immunocompromised hosts. The binding of P. carinii to alveolar epithelial cells and extracellular matrix constituents such as fibronectin and vitronectin is a central feature of infection, which initiates proliferation of the organism. Herein, we demon...

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Detalhes bibliográficos
Main Authors: Kottom, Theodore J., Köhler, Julia R., Thomas, Charles F., Fink, Gerald R., Limper, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC219549/
https://ncbi.nlm.nih.gov/pubmed/14573668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6463-6471.2003
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