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Lung Epithelial Cells and Extracellular Matrix Components Induce Expression of Pneumocystis carinii STE20, a Gene Complementing the Mating and Pseudohyphal Growth Defects of ste20 Mutant Yeast

Pneumocystis carinii causes severe pneumonia in immunocompromised hosts. The binding of P. carinii to alveolar epithelial cells and extracellular matrix constituents such as fibronectin and vitronectin is a central feature of infection, which initiates proliferation of the organism. Herein, we demon...

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Main Authors: Kottom, Theodore J., Köhler, Julia R., Thomas, Charles F., Fink, Gerald R., Limper, Andrew H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC219549/
https://ncbi.nlm.nih.gov/pubmed/14573668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6463-6471.2003
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