Recombinant Leishmania major Secreting Biologically Active Granulocyte-Macrophage Colony-Stimulating Factor Survives Poorly in Macrophages In Vitro and Delays Disease Development in Mice

Leishmania is an intracellular pathogen that replicates inside macrophages. Activated macrophages produce a specific subset of cytokines that play an important role in the control of Leishmania infections. As part of our interest in developing suicide parasites that produce abortive infections for t...

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Pubblicato in:	Infect Immun
Autori principali:	Dumas, Carole, Muyombwe, Anthony, Roy, Gaétan, Matte, Claudine, Ouellette, Marc, Olivier, Martin, Papadopoulou, Barbara
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14573672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.11.6499-6509.2003
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