Recombinant Leishmania major Secreting Biologically Active Granulocyte-Macrophage Colony-Stimulating Factor Survives Poorly in Macrophages In Vitro and Delays Disease Development in Mice

Leishmania is an intracellular pathogen that replicates inside macrophages. Activated macrophages produce a specific subset of cytokines that play an important role in the control of Leishmania infections. As part of our interest in developing suicide parasites that produce abortive infections for t...

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Bibliographische Detailangaben
Hauptverfasser: Dumas, Carole, Muyombwe, Anthony, Roy, Gaétan, Matte, Claudine, Ouellette, Marc, Olivier, Martin, Papadopoulou, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC219543/
https://ncbi.nlm.nih.gov/pubmed/14573672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6499-6509.2003
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