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Effects of genomic context and chromatin structure on transcription-coupled and global genomic repair in mammalian cells

It has been long recognized that in mammalian cells, DNA damage is preferentially repaired in the transcribed strand of transcriptionally active genes. However, recently, we found that in Chinese hamster ovary (CHO) cells, UV-induced cyclobutane pyrimidine dimers (CPDs) are preferentially repaired i...

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Bibliographic Details
Main Authors: Feng, Zhaohui, Hu, Wenwei, Chasin, Lawrence A., Tang, Moon-shong
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC219485/
https://ncbi.nlm.nih.gov/pubmed/14530438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg808
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