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Use of locked nucleic acid oligonucleotides to add functionality to plasmid DNA
The available reagents for the attachment of functional moieties to plasmid DNA are limiting. Most reagents bind plasmid DNA in a non-sequence- specific manner, with undefined stoichiometry, and affect DNA charge and delivery properties or involve chemical modifications that abolish gene expression....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC219479/ https://ncbi.nlm.nih.gov/pubmed/14530430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg801 |
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