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The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells
Bortezomib is a novel anti-cancer agent which has shown promising activity in non-small lung cancer (NSCLC) patients. However, only a subset of patients respond to this treatment. We show that NSCLC cell lines are differentially sensitive to bortezomib, IC(50 )values ranging from 5 to 83 nM. The apo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194734/ https://ncbi.nlm.nih.gov/pubmed/18021420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-73 |
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