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TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

BACKGROUND: Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to chemotherapy shown in this type of tumor. The aim of the present study was to investigate the mechanism of caspase-9 inhibition, with a fo...

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Detalhes bibliográficos
Main Authors: Checinska, Agnieszka, Giaccone, Giuseppe, Hoogeland, Bas SJ, Ferreira, Carlos G, Rodriguez, Jose A, Kruyt, Frank AE
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538619/
https://ncbi.nlm.nih.gov/pubmed/16796750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-166
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