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GRP94 (gp96) and GRP94 N-Terminal Geldanamycin Binding Domain Elicit Tissue Nonrestricted Tumor Suppression

In chemical carcinogenesis models, GRP94 (gp96) elicits tumor-specific protective immunity. The tumor specificity of this response is thought to reflect immune responses to GRP94-bound peptide antigens, the cohort of which uniquely identifies the GRP94 tissue of origin. In this study, we examined th...

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Bibliographic Details
Main Authors: Baker-LePain, Julie C., Sarzotti, Marcella, Fields, Timothy A., Li, Chuan-Yuan, Nicchitta, Christopher V.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194266/
https://ncbi.nlm.nih.gov/pubmed/12461080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020436
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