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The messenger and the message: gp96 (GRP94)-peptide interactions in cellular immunity

Vaccination of mice with tumor-derived stress proteins, such as Hsp70 and gp96 (GRP94), can elicit antitumor immune responses, yielding a marked suppression of tumor growth and metastasis. The molecular basis for this response is proposed to reflect a peptide-binding function for these proteins. In...

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Autors principals: Nicchitta, Christopher V., Carrick, Deanna M., Baker-LePain, Julie C.
Format: Artigo
Idioma:Inglês
Publicat: Cell Stress Society International 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065271/
https://ncbi.nlm.nih.gov/pubmed/15633290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-62.1
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