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CCR5 Expression Influences the Progression of Human Breast Cancer in a p53-dependent Manner

Chemokines are implicated in tumor pathogenesis, although it is unclear whether they affect human cancer progression positively or negatively. We found that activation of the chemokine receptor CCR5 regulates p53 transcriptional activity in breast cancer cells through pertussis toxin–, JAK2-, and p3...

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Detalhes bibliográficos
Main Authors: Mañes, Santos, Mira, Emilia, Colomer, Ramón, Montero, Sagrario, Real, Luis M., Gómez-Moutón, Concepción, Jiménez-Baranda, Sonia, Garzón, Alfredo, Lacalle, Rosa Ana, Harshman, Keith, Ruíz, Agustín, Martínez-A., Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194244/
https://ncbi.nlm.nih.gov/pubmed/14597737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030580
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