Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation

Thrombospondin 1 (TSP) elicits potent antiinflammatory activities in vivo, as evidenced by persistent, multiorgan inflammation in TSP null mice. Herein, we report that DCs represent an abundant source of TSP at steady state and during activation. Human monocyte-derived immature dendritic cells (iDCs...

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Bibliographische Detailangaben
Hauptverfasser: Doyen, Virginie, Rubio, Manuel, Braun, Deborah, Nakajima, Toshiaru, Abe, Jun, Saito, Hirohisa, Delespesse, Guy, Sarfati, Marika
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194231/
https://ncbi.nlm.nih.gov/pubmed/14568985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030705
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