Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation

Thrombospondin 1 (TSP) elicits potent antiinflammatory activities in vivo, as evidenced by persistent, multiorgan inflammation in TSP null mice. Herein, we report that DCs represent an abundant source of TSP at steady state and during activation. Human monocyte-derived immature dendritic cells (iDCs...

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Detalhes bibliográficos
Main Authors: Doyen, Virginie, Rubio, Manuel, Braun, Deborah, Nakajima, Toshiaru, Abe, Jun, Saito, Hirohisa, Delespesse, Guy, Sarfati, Marika
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194231/
https://ncbi.nlm.nih.gov/pubmed/14568985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030705
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