Prostaglandin D(2) Reinforces Th2 Type Inflammatory Responses of Airways to Low-dose Antigen through Bronchial Expression of Macrophage-derived Chemokine

PGD(2), a lipid mediator released from mast cells, is known to participate in allergic reactions. However, the mechanism by which PGD(2) contributes to such reactions remains unclear. We established a novel experimental model of asthma that permitted direct assessment of the role of PGD(2) in airway...

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Main Authors: Honda, Kyoko, Arima, Masafumi, Cheng, Gang, Taki, Shinsuke, Hirata, Hirokuni, Eda, Fukiko, Fukushima, Fumiya, Yamaguchi, Bunpei, Hatano, Masahiko, Tokuhisa, Takeshi, Fukuda, Takeshi
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194171/
https://ncbi.nlm.nih.gov/pubmed/12925672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022218
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