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Identification of a Pre-BCR Lacking Surrogate Light Chain

SLP-65(−/−) pre-B cells show a high proliferation rate in vitro. We have shown previously that λ5 expression and consequently a conventional pre-B cell receptor (pre-BCR) are essential for this proliferation. Here, we show that pre-B cells express a novel receptor complex that contains a μ heavy cha...

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Hlavní autoři: Su, Yu-wen, Flemming, Alexandra, Wossning, Thomas, Hobeika, Elias, Reth, Michael, Jumaa, Hassan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194143/
https://ncbi.nlm.nih.gov/pubmed/14638847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031428
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