Lymphotoxin Is Required for Maintaining Physiological Levels of Serum IgE That Minimizes Th1-mediated Airway Inflammation

Although elevated levels of IgE in asthmatic patients are strongly associated with lung infiltration by activated T helper (Th) 2 cells, the physiological role of immunoglobulin E (IgE) in the airway remains largely undefined. Lymphotoxin-deficient α (LTα(−/−)) mice exhibit increased airway inflamma...

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Autori principali: Kang, Hyung-Sik, Blink, Sarah E., Chin, Robert K., Lee, Youjin, Kim, Oliver, Weinstock, Joel, Waldschmidt, Thomas, Conrad, Daniel, Chen, Bohao, Solway, Julian, Sperling, Anne I., Fu, Yang-Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194142/
https://ncbi.nlm.nih.gov/pubmed/14638845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021784
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