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IgE/antigen-mediated enhancement of IgE production is a mechanism underlying the exacerbation of airway inflammation and remodelling in mice

IgE is known to enhance some antibody responses to specific antigens, but whether this contributes to allergic asthma remains unclear. We have previously found that repeated antigen challenges in mice sensitized with antigen-specific IgE monoclonal antibody (mAb) exacerbated airway inflammation and...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Mizutani, Nobuaki, Nabe, Takeshi, Yoshino, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264914/
https://ncbi.nlm.nih.gov/pubmed/24995892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12355
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