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Superior Protection against Malaria and Melanoma Metastases by a C-glycoside Analogue of the Natural Killer T Cell Ligand α-Galactosylceramide

α-Galactosylceramide (α-GalCer) is a glycolipid that stimulates natural killer T cells to produce both T helper (Th) 1 and Th2 cytokines. This property enables α-GalCer to ameliorate a wide variety of infectious, neoplastic, and autoimmune diseases; however, its effectiveness against any one disease...

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Bibliographic Details
Main Authors: Schmieg, John, Yang, Guangli, Franck, Richard W., Tsuji, Moriya
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194137/
https://ncbi.nlm.nih.gov/pubmed/14657217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031192
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