Alveolar Macrophage–mediated Killing of Pneumocystis carinii f. sp. muris Involves Molecular Recognition by the Dectin-1 β-Glucan Receptor

Innate immune mechanisms against Pneumocystis carinii, a frequent cause of pneumonia in immunocompromised individuals, are not well understood. Using both real time polymerase chain reaction as a measure of organism viability and fluorescent deconvolution microscopy, we show that nonopsonic phagocyt...

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Detalhes bibliográficos
Main Authors: Steele, Chad, Marrero, Luis, Swain, Steve, Harmsen, Allen G., Zheng, Mingquan, Brown, Gordon D., Gordon, Siamon, Shellito, Judd E., Kolls, Jay K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194130/
https://ncbi.nlm.nih.gov/pubmed/14657220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030932
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