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Regulation of Cyclooxygenase-2 Expression by the Translational Silencer TIA-1
The cyclooxygenase-2 (COX-2) enzyme catalyzes the rate-limiting step of prostaglandin formation in inflammatory states, and COX-2 overexpression plays a key role in carcinogenesis. To understand the mechanisms regulating COX-2 expression, we examined its posttranscriptional regulation mediated throu...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194089/ https://ncbi.nlm.nih.gov/pubmed/12885872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030616 |
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