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Interleukin 21 Is a T Helper (Th) Cell 2 Cytokine that Specifically Inhibits the Differentiation of Naive Th Cells into Interferon γ–producing Th1 Cells

The cytokine potential of developing T helper (Th) cells is directly shaped both positively and negatively by the cytokines expressed by the effector Th cell subsets. Here we find that the recently identified cytokine, interleukin (IL)-21, is preferentially expressed by Th2 cells when compared with...

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Autori principali: Wurster, Andrea L., Rodgers, Vikki L., Satoskar, Abhay R., Whitters, Matthew J., Young, Deborah A., Collins, Mary, Grusby, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194031/
https://ncbi.nlm.nih.gov/pubmed/12370258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020620
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