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Interferon γ Is Required for Activation-induced Death of T Lymphocytes

The effector cytokine interferon γ (IFN-γ) may play a role in T cell homeostasis. We have examined the requirement for IFN-γ in one mechanism that regulates T cell expansion and survival, activation-induced cell death (AICD). CD4(+) T cells lacking IFN-γ or the Stat1 transcription factor are resista...

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Detalhes bibliográficos
Main Authors: Refaeli, Yosef, Van Parijs, Luk, Alexander, Stephen I., Abbas, Abul K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194022/
https://ncbi.nlm.nih.gov/pubmed/12370261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020666
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