Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity

Constitutive nuclear nuclear factor (NF)-κB activity is observed in a variety of hematopoietic and solid tumors. Given the distinctive role of constitutive NF-κB for Hodgkin and Reed-Sternberg (HRS) cell viability, we performed molecular profiling in two Hodgkin's disease (HD) cell lines to ide...

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Hauptverfasser: Hinz, Michael, Lemke, Petra, Anagnostopoulos, Ioannis, Hacker, Christine, Krappmann, Daniel, Mathas, Stephan, Dörken, Bernd, Zenke, Martin, Stein, Harald, Scheidereit, Claus
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2002
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194004/
https://ncbi.nlm.nih.gov/pubmed/12208876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020062
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