B Cell–specific Transgenic Expression of Bcl2 Rescues Early B Lymphopoiesis but Not B Cell Responses in BOB.1/OBF.1-deficient Mice

Mice deficient for the transcriptional coactivator BOB.1/OBF.1 show several defects in B cell differentiation. Numbers of immature transitional B cells in the bone marrow are reduced and fewer B cells reach the periphery. Furthermore, germinal center B cells are absent and marginal zone (MZ) B lymph...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Brunner, Cornelia, Marinkovic, Dragan, Klein, Jörg, Samardzic, Tatjana, Nitschke, Lars, Wirth, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2003
Assuntos:
Brief Definitive Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193979/
https://ncbi.nlm.nih.gov/pubmed/12732662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022014
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares