Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer

Chronic inflammation contributes to carcinogenesis, but the underlying mechanisms are poorly understood. We report that aged granulocyte-macrophage colony stimulating factor (GM-CSF)-deficient mice develop a systemic lupus erythematosis (SLE)-like disorder associated with the impaired phagocytosis o...

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Detalhes bibliográficos
Main Authors: Enzler, Thomas, Gillessen, Silke, Manis, John P., Ferguson, David, Fleming, James, Alt, Frederick W., Mihm, Martin, Dranoff, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193978/
https://ncbi.nlm.nih.gov/pubmed/12732663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021258
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