Enhanced Antitumor Immunity in Mice Deficient in CD69

We investigated the in vivo role of CD69 by analyzing the susceptibility of CD69−/− mice to tumors. CD69−/− mice challenged with MHC class I(−) tumors (RMA-S and RM-1) showed greatly reduced tumor growth and prolonged survival compared with wild-type (WT) mice. The enhanced anti–tumor response was N...

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Main Authors: Esplugues, Enric, Sancho, David, Vega-Ramos, Javier, Martínez-A, Carlos, Syrbe, Uta, Hamann, Alf, Engel, Pablo, Sánchez-Madrid, Francisco, Lauzurica, Pilar
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193974/
https://ncbi.nlm.nih.gov/pubmed/12732655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021337
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