CD69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis

CD69 is induced after activation of leukocytes at inflammatory sites, but its physiological role during inflammation remains unknown. We explored the role of CD69 in autoimmune reactivity by analyzing a model of collagen-induced arthritis (CIA) in WT and CD69-deficient mice. CD69(–/–) mice showed hi...

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Detalhes bibliográficos
Main Authors: Sancho, David, Gómez, Manuel, Viedma, Fernando, Esplugues, Enric, Gordón-Alonso, Mónica, Angeles García-López, María, de la Fuente, Hortensia, Martínez-A, Carlos, Lauzurica, Pilar, Sánchez-Madrid, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193672/
https://ncbi.nlm.nih.gov/pubmed/12975472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319112
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