NIK-dependent RelB Activation Defines a Unique Signaling Pathway for the Development of Vα14i NKT Cells

A defect in RelB, a member of the Rel/nuclear factor (NF)-κB family of transcription factors, affects antigen presenting cells and the formation of lymphoid organs, but its role in T lymphocyte differentiation is not well characterized. Here, we show that RelB deficiency in mice leads to a selective...

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Autori principali: Elewaut, Dirk, Shaikh, Raziya B., Hammond, Kirsten J. L., De Winter, Hilde, Leishman, Andrew J., Sidobre, Stephane, Turovskaya, Olga, Prigozy, Theodore I., Ma, Lisa, Banks, Theresa A., Lo, David, Ware, Carl F., Cheroutre, Hilde, Kronenberg, Mitchell
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193960/
https://ncbi.nlm.nih.gov/pubmed/12810685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030141
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