CD1d-expressing Dendritic Cells but Not Thymic Epithelial Cells Can Mediate Negative Selection of NKT Cells

Natural killer T (NKT) cells are a unique immunoregulatory T cell population that is positively selected by CD1d-expressing thymocytes. Previous studies have shown that NKT cells exhibit autoreactivity, which raises the question of whether they are subject to negative selection. Here, we report that...

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Detalhes bibliográficos
Main Authors: Chun, Taehoon, Page, Michael J., Gapin, Laurent, Matsuda, Jennifer L., Xu, Honglin, Nguyen, Hanh, Kang, Hyung-Sik, Stanic, Aleksandar K., Joyce, Sebastian, Koltun, Walter A., Chorney, Michael J., Kronenberg, Mitchell, Wang, Chyung-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193895/
https://ncbi.nlm.nih.gov/pubmed/12682110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021366
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