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Complementary Role of CD4(+) T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8(+) T Cells
MHC class I–restricted tumor antigens can be presented to CD8(+) T cells by two distinct pathways: via direct and indirect presentation. The relative contribution of these two pathways toward the initial activation of tumor antigen–specific CD8(+) T cells and their subsequent tumor rejection is stil...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193872/ https://ncbi.nlm.nih.gov/pubmed/12695490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021804 |
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