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T Cell Receptor Gene Rearrangement Lineage Analysis Reveals Clues for the Origin of Highly Restricted Antigen-specific Repertoires

Due to ordered, stage-specific T cell receptor (TCR)-β and -α locus gene rearrangements and cell division during T cell development, a given, ancestral TCR-β locus VDJ rearrangement might be selected into the mature T cell repertoire as a small cohort of “half-sibling” progeny expressing identical T...

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Hlavní autoři: Hamrouni, Abdelbasset, Aublin, Anne, Guillaume, Philippe, Maryanski, Janet L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193826/
https://ncbi.nlm.nih.gov/pubmed/12615901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021945
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