Specificity of Tissue Transglutaminase Explains Cereal Toxicity in Celiac Disease

Celiac disease is caused by a selective lack of T cell tolerance for gluten. It is known that the enzyme tissue transglutaminase (tTG) is involved in the generation of T cell stimulatory gluten peptides through deamidation of glutamine, the most abundant amino acid in gluten. Only particular glutami...

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Detalhes bibliográficos
Main Authors: Vader, L. Willemijn, de Ru, Arnoud, van der Wal, Yvonne, Kooy, Yvonne M.C., Benckhuijsen, Willemien, Mearin, M. Luisa, Drijfhout, Jan Wouter, van Veelen, Peter, Koning, Frits
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193762/
https://ncbi.nlm.nih.gov/pubmed/11877487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20012028
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